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Photo courtesy of Larry Holle

  • Alzheimer's Therapy
  • Age-related diseases, such as Alzheimer’s, are ultimately caused by cell aging. In the case of Alzheimer’s disease, microglial cells age over time and trigger a cascade of pathology. The microglia support neurons metabolically. As microglial cells divide over time, their telomeres shorten and gene expression shifts.
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  • Investor sponsored research
  • Current investors are underwriting FDA-sponsored phase 0 through phase 2 human trials of telomerase therapy as a treatment for Alzheimer’s disease. Although the current animal data is remarkable, the FDA may well require that we demonstrate additional safety trials before permitting first-in-human trials.
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